Accounting for genetic interactions is necessary for accurate prediction of extreme phenotypic values of quantitative traits in yeast

نویسندگان

  • Simon K. G. Forsberg
  • Joshua S. Bloom
  • Meru J. Sadhu
  • Leonid Kruglyak
  • Örjan Carlborg
چکیده

Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. Department of Human Genetics, University of California, Los Angeles, Los Angeles, California 90095, USA. Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, California 90095, USA. Department of Biological Chemistry, University of California, Los Angeles, California 90095, USA.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

اهمیت خویشاوندی ژنتیکی و رکورد فنوتیپی بر صحت ژنومی داده‌های جانهی شبیه‌ سازی شده با استفاده از مدل های حیوانی در حضور اثرات متقابل ژنوتیپ و محیط

The objective of this study was to investigate the role of genetic relationships between training and validation set with considering different ratio of phenotypic records of training set on accuracy of genomic prediction via animal models containing genotype × environment interactions in simulated imputation data. For this purpose, four different scenarios using 15k density containing differen...

متن کامل

بررسی تغییرات فنوتیپی و ژنتیکی صفات اقتصادی میش در یک گله گوسفند لری بختیاری

In this study 5025 records from the Lori-Bakhtiari sheep stud were used to predict phenotypic, genetic and environmental change in ewe traits from 1989 to 2004. Best linear unbiased prediction (BLUP) of breeding values were estimated by Drivative Free Restricted Maximum Likelihood (DFREML) procedure using single and multi-trait animal model. Phenotypic, genetic and environmental trends were cal...

متن کامل

بررسی تغییرات فنوتیپی و ژنتیکی صفات اقتصادی میش در یک گله گوسفند لری بختیاری

In this study 5025 records from the Lori-Bakhtiari sheep stud were used to predict phenotypic, genetic and environmental change in ewe traits from 1989 to 2004. Best linear unbiased prediction (BLUP) of breeding values were estimated by Drivative Free Restricted Maximum Likelihood (DFREML) procedure using single and multi-trait animal model. Phenotypic, genetic and environmental trends were cal...

متن کامل

Estimation of genetic and phenotypic trends for body weight traits of sheep in Guilan province of Iran

The main objective of the present study was to estimate genetic and phenotypic trends for body weight traits in Guilan province sheep. Traits included were birth weight (BW, n=14,549), 3-month weight (3MW, n=13,109) and 6-month weight (6MW, n=10,141). Data and pedigree information used in this study were collected during 1994 to 2011 by the Agricultural Organization of Guilan province in Iran. ...

متن کامل

ارزیابی صحت پیش‌بینی ژنومی در معماری‌های مختلف ژنومی صفات کمی و آستانه‌ای با جانهی داده‌های ژنومی شبیه‌سازی‌شده، توسط روش جنگل تصادفی

Genomic selection is a promising challenge for discovering genetic variants influencing quantitative and threshold traits for improving the genetic gain and accuracy of genomic prediction in animal breeding. Since a proportion of genotypes are generally uncalled, therefore, prediction of genomic accuracy requires imputation of missing genotypes. The objectives of this study were (1) to quantify...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016